Hand washing Compendium for Low Resource Settings: A Living Document

Frequent and proper handwashing with soap is one of the most important measures that can be used to prevent the spread of the COVID-19 virus, along with physical distancing, avoiding touching one’s face (eyes, nose and mouth) and practicing good respiratory hygiene. Yet 40 per cent of households lack access to a facility with soap and water, of which 18 per cent have no facility whatsoever (WHO and UNICEF, 2020). 
 In response to the global COVID-19 pandemic, the Sanitation Learning Hub at the Institute of Development Studies has rapidly developed the Handwashing Compendium for Low Resource Settings that can be used to support increased access to facilities and promote positive handwashing behaviours. 
 The compendium provides guidance on low-cost handwashing facilities that can be widely used in low and middle-income countries. We hope that this can be shared extensively as governments and agencies tackle the crisis in low and middle-income countries where handwashing facilities are urgently needed in households, communities, schools and healthcare facilities. 
 The compendium includes information and further reading on: • Handwashing facilities – including facilities that are accessible for all. • Environmental cues to reinforce handwashing behaviours. • Physical distancing hygiene promotion. 
 Download report.

Natures UV light to UV-C LED for COVID 19

Like electricity, ultraviolet light is as old as the universe. It just took someone to notice. In 1877, British Physiologist Arthur Downes and scientist Thomas P. Blunt noticed. They put solution-filled test tubes outside and discovered that sunlight could kill and inhibit the development of pathogenic bacteria.

Some 25 years later, the German Ophthalmologist Ernst Hertel built on this knowledge, determining that light in the UV-C wavelength, rather than UV-A or UV-B, is the most effective for killing microorganisms. Around the same time, the Danish Professor Niels Finsen won the Nobel Prize for Physiology in recognition of his work in treating lupus vulgaris bacteria on human skin with concentrated light (See image). In the 1930s and 1940s, William F. Wells, a Harvard University sanitary engineer, made a significant stride in the knowledge and application of UV-C light for disinfection by proving its effectiveness in killing airborne microorganisms. It was Wells who discovered that bacteria and viruses can be transmitted to people through the air they breathe.

UV has been proven effective against a broad spectrum of microorganisms. Viruses contain RNA or DNA and are thus susceptible to irradiation. Bacteria and fungi both contain DNA and are similarly vulnerable to UV light. Spores are also susceptible to UV. With the longstanding use of UV for disinfection, there is a plethora of information regarding dosages necessary to inactivate different microorganisms. Bacteria are generally easier to inactivate than viruses, with fungi and spores being even harder to inactivate with UV.  (Read the paper)

ARI researchers develop `Bug Sniffer'

Researchers at the Agharkar Research Institute (ARI), Pune, an autonomous institute under the Department of Science &Technology, Govt. of India, have developed a sensitive and low-cost sensor to rapidly detect bacteria.  The portable device can detect as low as ten bacterial cells from a sample size of one milliliter in just 30 minutes. At present, they are working on a method for simultaneous separation and detection of Escherichia coli and Salmonella typhimurium.  Lead researcher Dr Dhananjay Bodas and his team from ARI call it the ‘bug sniffer,’ which is a biosensor that uses synthetic peptides, magnetic nanoparticles, and quantum dots to detect the presence of bacteria, providing a cost- and time-effective way of screening water and foodborne pathogens. The researchers also developed a chip comprising of microchannels made from copper wires and poly (dimethylsiloxane) The conventional techniques available for pathogen detection are less sensitive and cannot detect low cell numbers, besides being time-consuming and laborious whereas the ARI device, can detect pathogens with a limit of detection of 10 cells per 1 mL within 30 minutes.

Hot air sealing machine for PPE

There are reports that India's efforts to make PPEs in large quantity are hampered by absence of locally produced Hot Air Sealing machines. In this article, Prabir Jana, Professor, NIFT Delhi (India) with inputs from UNIK Technologyz (India) and Tukatech, Inc. (USA) demystify the making of body coverall on an industrial scale.

Hydrogen on Demand -long road to technology commercialisation.

In 1967, while working as a researcher at IBM, Woodall discovered that liquid alloys of aluminum and gallium spontaneously produce hydrogen if mixed with water. The research, which focused on developing new semiconductors for computers and electronics, led to advances in optical-fiber communications and light-emitting diodes, making them practical for everything from DVD players to television remote controls and new types of lighting displays. That work also led to development of advanced transistors for cell phones and components in solar cells powering space modules like those used on the Mars rover, earning Woodall the 2001 National Medal of Technology from President George W. Bush. Also while at IBM, Woodall and research engineer Jerome Cuomo were issued a U.S. patent in 1982 for a "solid state, renewable energy supply." The patent described their discovery that when aluminum is dissolved in liquid gallium just above room temperature, the liquid alloy readily reacts with water to form hydrogen, alumina and heat.
Woodall moved to Purdue university and continued to work on the aluminium alloy. His team succeeded in developing technology that produces hydrogen by adding water to an alloy of aluminum and gallium. When water is added to the alloy, the aluminum splits water by attracting oxygen, liberating hydrogen in the process. The Purdue researchers are developing a method to create particles of the alloy that could be placed in a tank to react with water and produce hydrogen on demand. The Purdue Research Foundation holds title to the primary patent, which has been filed with the U.S. Patent and Trademark Office and is pending. An Indiana startup company, AlGalCo LLC., has received a license in 2007 for the exclusive right to commercialize the process.
AlGalCo founder and president  Kurt Koehler is a businessman, not a chemist. He graduated with a degree in marketing and management from IU and went on to earn a Master's in European History. As luck would have it, an encounter with Purdue representatives at the Indiana State Fair piqued his interest and ultimately led him to Purdue professor Jerry Woodall, who had developed the aluminum alloy technology. After 14 years of beta testing product is rolled out for Carmel's city fleet. 

THE LONG ROAD TO TECHNOLOGY COMMERCIALIZATION- CASE OF FUEL CELLS FOR TRUCK

Geoffrey Ballard, CM, OBC (16 October 1932 – 2 August 2008) was a Canadian geophysicist and businessman. One of the studies he had been involved in at the U.S. Federal Energy Conservation Research office was on electric cars powered by conventional lead-acid batteries. Ballard had  met Ralph Schwartz in Arizona, who introduced him to the idea of using lithium batteries in place of lead-acid, as they would be much lighter. However, at the time, lithium batteries were not able to be recharged. Schwartz convinced Ballard that they should study the problem, and Ballard cashed in his pension to buy a portion of their new joint venture, American Energizer. Schwartz and Ballard were introduced to Keith Prater at the University of Texas chemistry department, and sold him on the idea of developing a new rechargeable lithium battery technology with them. Prater was able to quickly determine that no one knew what the product of the lithium-salt reactions in existing batteries were, and guessed that it was lithium dithionite, which he was able to synthesize. Working in a trailer, Ballard and Schwartz built a simple battery and Prater brought a sample of the lithium dithionite, and when they were placed together and charged, a weak current was produced. After further development the system was able to be recharged about a dozen times. Ballard had always wanted to return to Canada, so Schwartz sold his interest in the battery technology to Ballard for $1, while Ballard sold his interest in Schwartz's latest venture, a mechanical anti-lock braking system for the same $1. In 1979 Ballard moved to Vancouver and became president and CEO of Ultra Energy.

In 1983, Ballard, Prater and Paul Howard started looking for new ideas for their development side to work on as the funds for the battery project dried up. Among a variety of ideas were a number of attempts to find government funding, which eventually led them to a Department of National Defense (DND) request for proposals for bids to produce a low-cost solid polymer fuel cell. Now known as PEM's, these cells had only been used commercially in Project Gemini and a few other space probes, and General Electric gave up on the technology when NASA moved onto other fuel cell designs for Project Apollo and the Space Shuttle. Although a number of attempts had been made to lower the high cost of PEM cells since then, none had been commercially successful. They won the $500,000 contract, which called for them to provide three prototype cells that produced between 50 and 150 watts and be ready in 28 months. After meeting the requirements, they won a follow-up contract, and it was during this project, in 1986, when they reached a milestone of producing four times as much energy per unit volume as any previous fuel cell.

Feeling the technology was ready for commercial use, in 1989 Ballard raised $4 million in public money from the British Columbia government to build a fuel cell powered bus, introducing it at Science World in 1993. He took the bus to energy fairs around the world, and Daimler-Chrysler and Ford invested $750 million to buy a one-third stake in the newly public Ballard Power Systems. Ballard told Time in 1999 that the fuel-cell cars should become economical by 2010.

Dr. Sean MacKinnon was Senior Research Scientist at Ballard Power Systems , where he drafted, negotiated and managed a High Temperature PEM research project funded through Natural Resources Canada, in collaboration with NRC-IFCI. Later he worked at General Motors Fuel cell Research lab as Principle Investigator and program manager for collabative membrane development programs with strategic partners. He continued work at National Research Council of Canada and developed proton exchange membranes for automotive polymer electrolyte membrane fuel cells. Dr Deve Ghosh was Director R&D at NRC Institute for Fuel Cell Innovation in Vancouver, BC, development of Low cost durable PEMFC Pt alloy catalyst on non-carbon support ( $10M 3 year project with Ballard & AFCC) was one of major R&D project.

Mr. David Leger, has been working on the technology with inventor and engineer Mr. Greg Montie B.Eng for over a decade. Greg was a Director on the board for PowerDisc Technology, and has performed lead technical roles at Cummins Westport natural gas engines, dPoint energy recovery systems, and PowerDisc hydrogen fuel cells. During this time, he had invented and filed 10 patents resulting in a number of commercial successes. Invented and developed the patented the eFlow hydrogen fuel cell. Specifically, eFlow is an exponentially delineating hydrogen fuel cell, and is currently considered to have one of the highest specific power outputs and the only substantial fuel cell to claim uniform current density.

In 2005 Inventors Greg Montie, Rodney Bruce Redlich and David Earl Leger  filed patent for Fuel cell cathode flow field  ,Patent number: 7838169  assigned to Power Disc Development Corporation. A fuel cell cathode flow field has multiple channels each with a cross-sectional area that varies along the length of the channel such that oxygen availability at every lengthwise position along the channel is kept substantially constant for a given channel length and air stoichiometry ratio. Each channel comprises a flat floor with substantially constant depth and a pair of side walls extending upwardly from the floor; the side walls each taper inwards from channel inlet to outlet with a convex curve relative to the channel centreline. Achieving substantially uniform oxygen availability throughout the flow field results in substantially uniform current density throughout the flow field, which is desirable for efficient fuel cell operation and improved performance.

PowerDisc Development Corporation is a fuel cell company based in Vancouver BC with David Leger co- inventor of eFlow Fuel Technology was CEO and President and Dr Sean MacKinnon is Chief Scientist. PowerDisc has also been selected as a participant in the Canadian Technology Accelerator Program (CTA). Sponsored by the Canadian Department of Foreign Affairs, Trade and Development, and administered by the consular trade commissioner in Colorado, the CTA program is focused on assisting Canadian technology companies to enter the United States marketplace while providing  them with improved access to funding, customers and networks of expertise.

PowerDisc is later renamed as Loop Energy Inc in 2016  to  mark the introduction of the company's zero­emission powertrain for heavy­duty transportation. Cummins is a strategic partner and Loop will supply Cummins with its 30-kilowatt (kW) and 50-kW FC-REX range-extender systems for use in Class 6-8 demonstration trucks. Loop has several demonstration programs underway. One involves retrofitting two Class 8 Peterbilt 579 long-haul trucks with fuel-cell/battery-electric drive system integrator TransPower. Those trucks will haul up to 80,000 pounds of freight throughout the San Diego and Los Angeles regions later this year.  In 2019 company has established a joint venture and non-exclusive license agreement with IN-Power, a leading power electronics supplier to the transport sector in China. In April 2020 Loop Energy, received a purchase order from a leading bus manufacturer in China to support the Nanjing municipal government's objective of replacing its existing 7000-unit battery-electric bus fleet with an improved battery-hydrogen hybrid alternative.

During this journey the firm received several grants in Canada. It was awarded a $7.5 million grant from Sustainable Development Technology Canada (SDTC) to accelerate deployment of the company's new zero-emission powertrain for heavy-duty trucks. Funding under Western Innovation  (WINN) Initiative contributed to commercialize and scale fuel cell range extender for heavy-duty Class 8 trucks and buses beginning in 2018.

Free E Book on Innovation

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Ambu bag Ventilator gets new life with COVID 19

Many innovators in India are working on this Ambu Bag deign with improvements as an alternate to expensive ventilator. Brief history of this product.

The original bag-valve-mask concept was developed in 1953 by the German doctor Holger Hesse and his partner Danish anesthetist Henning Ruben, following their initial work on a suction pump. Their resuscitator, named “Ambu” (Artificial Manual Breathing Unit), was manufactured and marketed in 1956 by their company.

The Danish manufacturer, Testa Laboratory made the first commercially produced Ambu bags in 1957. The company later changed its name to Ambu International. Many other companies now also make self-inflating “bag and mask” resuscitators, like the one shown here. These have become standard equipment in ambulances, hospital emergency rooms, and patient rooms.

A dozen ventilator prototypes at different stages have been developed in March 2020 alone by teams in different countries – and organising on Slack channels, Facebook groups, and GitHub repositories.Some of the most basic open-source ventilator models are based on an ‘ambu-bag’.

A word of caution:

The results of this review, however, found that the tested and peer-reviewed ventilator systems lacked complete documentation and that the current open systems that were documented were either at the very early stages of design or had undergone only early and rudimentary testing. With the considerably larger motivation of an ongoing pandemic, it is assumed these projects will garner greater attention and resources to make significant progress to reach a functional and easily replicated open source ventilator system. There is a large amount of technical future work needed to move open source ventilators up to the level considered adequate for scientific-grade equipment and further work still to reach medical-grade hardware. Future work is needed to achieve the potential of this approach not only on the technical side, but also by developing policies, updating regulations and securing funding mechanisms for the development and testing of open source ventilators for both the current COVID19 pandemic, as well as for future pandemics and for everyday use in low-resource settings.

WHO specifications-Products for Surveillance, Prevention & COVID 19

Download specifications:
WHO REFERENCE NUMBER: WHO/2019-nCoV/DCPv3/2020.4

Guide to local production of WHO-recommended Handrub Formulations

Part A is intended to guide a local producer in the actual preparation of the formulation.

Part B contains important safety and cost information and incorporates information from the WHO Guidelines on Hand Hygiene in Health Care (2009).

- Access the publication

Expression of Interest (EOI) for Co Developing and manufacturing Devices for COVID-19 Pandemic

Many technologies on offer from SCTIMST: https://www.sctimst.ac.in/COVID-19/

SCTIMST invites manufacturers/start ups/social groups who are interested in working with Institute to co-develop and manufacture medical devices on a fast track mode to support the distressing situation the epidemic COVID 19 has created. Please join us for development and manufacture of devices such as :

• Ambu bag based Ventilator
• Ventilator Sharing Kit
• Battery Operated Assistive Breathing Unit
• Isolation Pods
• Disposable Safety Face Shield
• Deployable Field Units

For further details, please contact Technology Business Division : tbd@sctimst.ac.in
Call us : Mr S. Balram (9249402311)/ Ms Sandhya C.G (9895098086)
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