A firm promoted by Dr Krishan Reddy manufacturing Stents, Catheters etc crossed a major mile stone with receipt of FDA approval. This is the dream project of Dr. A.P.J. Abdul Kalam, H.E. The President of India who was responsible for inventing the first indigenous Coronary Stent "Kalam-Raju Stent", India's first indigenously developed stent in the year 1998. This first Coil stent was marketed by Relisys Medical Devices Ltd. This was the first indigenously developed Stent by DRDO and CARE Group.The product was withdrawn in 2001 as coil stents were phased out world wide. Advanced version of the company's Drug-Eluting Stent (DES) has been designed to eliminate the existing drawbacks of the currently available polymer coated Drug-Eluting Stent. Relisys' new DES consists of a Cobalt-Chromium Stent, coated with a porous carbon/carbon composite nano-structured matrix containing the active drug. The coating was developed and provided by Blue Membranes, the Germany based company in material and surface engineering. The coating eliminates the use of polymers thus completely reducing tissue inflammation and reaction.The animal trials for this version of advanced DES were recently completed at the Cardiovascular Research Institute, Washington D.C.Clinical trial were carried out at All India Institute of Medical Sciences, New Delhi, Cardio-Thoracic Centre, Military Hospital, Pune, and CARE Hospitals, Hyderabad.