The ZyCoV-D is the world’s first and India’s indigenously developed
DNA based vaccine for COVID-19 to be administered in humans
including children and adults 12 years and above. This vaccine has
been developed in partnership with the Department of Biotechnology
(DBT), Government of India under the ‘Mission COVID Suraksha’ and
implemented by BIRAC, a PSU of DBT. This 3 dose vaccine which when injected produces the spike protein of the SARS-CoV-2 virus and elicits an immune response, which plays a vital role in protection from disease as well as viral clearance.Vaccine Technology Centre (VTC), vaccine research centre of the
Zydus group, Translational Health Science and Technology Institute
(THSTI), an autonomous institute of the DBT and Interactive Research
School for Health Affairs (IRSHA), Pune, GCLP Lab set up under the
DBT- National Biopharma Mission (NBM) also played a vital role in this
success story. The plug and play technology on which the plasmid DNA platform is based can be easily adapted to deal with mutations in the virus, such as those already occurring.
Read about the amazing journey: DBT publication
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